Just another day in Metropolis...
Professor Denison is just the tiniest bit crazy.
She was Lana Lang's professor at Hudson University, and Lana's number one fan. So when Lois "stole" Superman from Lana, well, she decided to take matters in to her own hands:
Anyway, it turns out that the emotional lobotomy is permanent--Lois breaks lunch dates with her sister, and is rude to widows. Ouch.
But she decides to fake still loving Superman, because, well, it's a good career move?!?
Oh, don't worry, fans. It turns out that Professor Denison's "emotional lobotomy" was really just advanced hypnosis, and Kal-El managed to cure Lois with a little super-dickery. The End.
Still haven't found a cure for the emotional lobotomy afflicting DC, though...
From Lois Lane #109 (1971)